Abstract
The current study aims to investigate the tissue lesions induced by Poppy anemone in pregnant mice. The administration of Poppy anemone (200,400 and 600 mg/kg) begins from days 7-8 of pregnancy. The results showed an increase in the rate of deaths and miscarriages in pregnant female mice with an increase in the concentration used. The uterine horns also showed a difference in the distribution of embryos, the appearance of bleeding cases and the accumulation of fatty materials. Some absorbed embryos also appeared. As for histological changes in the skin of the fetuses, there was edema around the hair follicles and between the collagenous fibers of the dermis layer and around the skin, sweat, and sebaceous glands, presence of edema between the epidermis layer and the dermis, congestion of capillaries, the divergence of collagen fibers in the dermis of the skin, hyperkeratosis of the epidermis, presence of hydrophilic degeneration in the spiny cell layer of the epidermis, rarefaction of the white fibers of the dermis and congestion of blood capillaries.
