The Synergistic Effects of Alkanna hirsutissima Boiled Extract and some Antibiotics on some Bacterial Species in Vitro and in Vivo
College Of Basic Education Research Journal,
2013, Volume 12, Issue 3, Pages 691-702
AbstractThe antibacterial effects of boiled aqueos extract of Alkanna hirsutissima on the bacteria Staph.aureus, Bacillus cereus, Klebsiella pneamoniae, Proteus mirabilis and the sensitivity of these bacteria to some antibiotics (Penicillin, Amoxycillin, Cefotaxime, Clindamycin, Ceftriaxone) were studied. The study also includes the Synergistic effects of Alkanna hirsutissima extract and antibiotics on the bacteria. The results showed that this extract possessed synergistic effects in all of these antibiotics in all the species of bacteria except Klebsiella pneumonia. The study also includes the In-vivo synergistic effects of this extract and cefotaxime in the treatment of experimentally infected wounds with Staph.aureus within 10 days compared with cefotaxime alone or boiled extract alone which was treated within 17 days.
Key words: Synergistic effects, plant extract, Alkanna hirsutissima, antibiotics.
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