The recent paper studies the impact of coccidiosis on blood levels of cattle since it is one of the parasites that attack both poultry and cattle epidemically and infect the intestine leading to big economical loss as well as high deaths of those animals. Due to the few number of relevant studies that present for the this parasite effect on blood level as well as the levels of anti-oxidation, Glutathione, I did such the study which includes 40 cows and 35 calves of 2-3 months of age from which a stool sample was taken plus a 5 mml blood sample. Next, I diagnosed the infected animal through testing the symptoms of those animals and examining the stool by both floating and smear methods directly to find the ovarian cysts of coccidiosis. Then, I determined the level of infection (the number of parasites per 1 gm of stool) by using Macmaster way so the animals were divided into two groups (infected and non-infected). After that, some biochemical tests were done to check the levels of Malondialdehyde (MDA) as a final outcome of lipid peroxidation using colorful TBA ase and to measure the absorption of ( 450 um) wavelength. Also, I divided the Glutathione (GSH) level in blood plasma using Elmanz method.