Keywords : Production

Sensitivity of Staphylococcus aureus and Klebsiella pneumoniae isolated from rhinosinusitis cases towards some antibiotics and their abilities of β-lactamase production

College Of Basic Education Research Journal, 2012, Volume 11, Issue 4, Pages 596-611

Twenty isolated of Klebsiella pneumonia and 44 isolated of Staphylococcus aureus were obtained from rhinosinsitis cases and biochemically characterized. The effect of some antibiotic were studied on both genera, Amikacin and Ciprofloxacin showed significant effect on the K.pneumoniae strains while it showed greater resistence towards Gentamicin and Rifampicin.The antibiotics Gentamicin, Vancomycin,Trimethoprim-sulfamethoxazole showed a great effect on S.aureus strains while it showed a greater resistence against the antibiotics Amoxicillin and Methicillin.The ability of these bacteria to produce β-lactamase & extended spectrum β-lactamase results showed that the strians of two types of bacteria had a great ability of β-lactamase production while small percentage of K.pneumoniae strians showed production of extended spectrum β-lactamase